【獲證專利公告】化學系王家蓁教授研究成果「一種苯酞類化合物用於製備替代/輔助高壓氧療法改善組織缺氧之醫藥組合物的用途」獲得美國發明專利!
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發明人 |
王家蓁教授 |
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系所 |
化學系 |
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專利名稱 |
一種苯酞類化合物用於製備替代/輔助高壓氧療法改善組織缺氧之醫藥組合物的用途 |
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證書號 |
US9,937,150 B2 |
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公告日期 |
107年4月10日 |
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專利摘要 |
The present invention relates to a method for substituting for or acting with the hyperbaric oxygen therapy to improve hypoxia, comprising the step of: administrating a phthalide compound to a subject in need thereof, wherein the phthalide compound can increase the oxygen release efficiency of blood hemoglobin (Hb) in the subject and further increase the cellular oxygenation level, and when the phthalide compound substitutes for or act with the hyperbaric oxygen therapy, the common adverse side effects of the hyperbaric oxygen therapy, such as barotrauma, decompression sickness and oxygen poisoning, are prevented. The phthalide compound is used to substitute for or act with 2,3-BPG, to modulate and decrease the oxygen affinity of hemoglobin (Hb), to increase the oxygen release efficiency of hemoglobin (Hb) to tissue cells, thereby achieving a normal cellular oxygenation level and maintaining the cellular oxygenation level in a normal range.
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技轉服務窗口 |
曾溫仁(分機2621) |
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